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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cytarabine and Histidine

supplement:

Histidine

Research Papers that Mention the Interaction

Thus, L-histidinol diminishes the myelocytoxicity otherwise associated with the in vivo use of agents such as cytosine arabinoside and 5-fluorouracil.
Anticancer research  •  1986  |  View Paper
It was previously demonstrated that L-histidinol , a structural analogue of the essential amino acid L-histidine, improves the specificity of cytarabine (ara-C) and 5-fluorouracil (FUra) in DBA/2J mice bearing intraperitoneal L 1210 leukemia.
Thus L-histidinol mediates a substantial increase in the specificities of ara-C and FUra in mice bearing an established bone marrow leukemic condition.
Journal of the National Cancer Institute  •  1985  |  View Paper