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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Cytarabine
supplement:
Genistein
Research Papers that Mention the Interaction
“… genistein … ara-C , two groups of severe combined immunodeficient mice were inoculated with NB4 and HL-60 cells, respectively, followed by treatment with either genistein or …. The combination treatment significantly inhibited tumor growth, and improved survival of NB4 (p = 0.0031) and HL-60 (p = 0.0007) xenograft mice.”
Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling.“The results further demonstrate that ara-C treatment is associated with a dose-dependent activation of p56/p53lyn and that ara-C-induced p56/p53lyn activity is blocked by the protein tyrosine inhibitors herbimycin A and genistein.”
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