“In this work, the main molecules responsible for generating chemoresistance to Ara-C in AML are … strategies to overcome it, such as the inclusion of molecules that can induce synergistic cytotoxicity with Ara-C (…, emodin , metformin and niclosamide), subtoxic concentrations of chemotherapy (… damage nonmalignant cells (heteronemin or hydroxyurea + azidothymidine).”