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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Cysteine
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“This suggests that vitamin B-6 status might affect cysteine and glutathione homeostasis, but it is unclear whether this occurs in humans.”
Plasma glutathione and cystathionine concentrations are elevated but cysteine flux is unchanged by dietary vitamin B-6 restriction in young men and women.“Endothelemia was increased furthermore by oral administration of cysteine and cystine and this increase was again inhibited by pyridoxine.”
“However, L-cysteine plus pyridoxial phosphate or GYY4137 significantly reduced it.”
Increase or Decrease Hydrogen Sulfide Exert Opposite Lipolysis, but Reduce Global Insulin Resistance in High Fatty Diet Induced Obese Mice“It is known that dietary vitamin B6 supplementation can increase the level of endogenous cysteine.”
“ Vitamin B6 supplementation increases the level of endogenous cysteine.”
“A stereospecific interaction between L-cysteine and PLP bound to the enzyme, forming one of the two possible diastereoisomers, is postulated.”
“The reaction between L-cysteine and PLP bound to the enzyme has a particular behaviour, different from all the other aminothiols.”
“Treating the enzyme with cysteine apparently affects the removal of pyridoxal phosphate and destroys the enzyme activity.”
“Conclusion: The result of this survey showed that the protective activity of L-cysteine and sodium hydrosulfate enhances in the presence of vitamin B6.”
“The gastroprotective activity of L-cysteine and sodium hydrosulfate in combination with vitamin B6 were higher than when administered alone (P<0.05).”
Protective effects of vitamin B6 alone and in combination with L-cysteine and NaHS on ethanol and indomethacin-induced gastric lesions in mice“In contrast, replacement of either Lys-37 or Lys-239 with cysteine caused a modest reduction in the inhibition caused by PLP (i.e., 31% and 20% loss of inhibition, respectively).”
“The active forms of vitamin B6 are essential coenzymes in the synthesis of l-cysteine and of other thiol compounds.”
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