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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cysteine
drug:
Sodium Sulfide
Research Papers that Mention the Interaction
“Additionally,in the presence of flurbiprofen, the H2S donors, NaHS and Na2S , mimicked the relaxations produced by L-cysteine , yielding IC50 values of 5.8 μM and 180 μM, espectively.”
Role of Hydrogen Sulfide Production in Inhibitory Action of L-Cysteine on Isolated Porcine Irides“L-cysteine (10−6–10–3 M) induced only … reaching 24 ± 6% at 10–3 M. Premixing L-cysteine (10–3 …) with Na2S and GYY4137 decreased Na2S relaxation and abolished GYY4137 relaxation, an effect prevented by … nitric oxide (NO) synthase inhibitor, L-NAME (Nω-nitro-L-arginine methyl ester).”
“The present findings suggest that L-cysteine by reaction with Na2S and GYY4137 and formation of sulfides, inhibits relaxations by these compounds.”
GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and KV7 Channel Blockers in Rat Small Mesenteric Arteries
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