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Last Updated: 2 years ago

Possible Interaction: Cysteine and Serine

supplement:

Cysteine

supplement:

Serine

Research Papers that Mention the Interaction

In addition, an SBD mutant with both cysteines mutated to serines loses its ability to promote MLKL polymerization.
Proceedings of the National Academy of Sciences  •  2020  |  View Paper
Blocking the cysteine α-amino group with a serine (SCNGRC) reduced both post-translational and degradation reactions.
Molecular pharmaceutics  •  2020  |  View Paper
Substitution of the conserved cysteine residue in the DNA binding domain of Bach1 to serine (C574S mutant) caused a refractory response to the diamide-mediated reactivation of the Bach1-suppressed reporter activity.
Free radical biology & medicine  •  2005  |  View Paper
When both cysteines were mutated into serines , normal MT1 receptor binding and activation were abolished.
Journal of pineal research  •  2005  |  View Paper
Mutation of either of the disulfide bridge‐constituting cysteines to serine resulted in a loss of ion channel activity whereas amino acid transport was unaffected.
The Journal of physiology  •  2000  |  View Paper
Site-directed mutagenesis of either cysteine 621 or 622 to serine residue was partially inhibitory, whereas mutation of both cysteine residues (621 and 622) completely abolished palmitoylation.
The Journal of biological chemistry  •  1994  |  View Paper
These include: 1) SATT's apparent low expression in ASC-containing tissues such as liver or placenta; 2) the lack of mutual inhibition between serine and cysteine ; and 3) the lack of trans-stimulation.
The Journal of biological chemistry  •  1993  |  View Paper
Substitution of serine for cysteine was associated with a reduction in the effectiveness of interleukin‐6 in both fibrinogen secretion assays.
Journal of leukocyte biology  •  1992  |  View Paper
Replacement of cysteines with serines reduced activity relative to cysteine-containing rIL-6 to about 20% in the rat hepatoma assay and about 3% in the mouse hybridoma assay, whereas activity in both of the human cell lines was reduced to less than 0.1%.
Journal of immunology  •  1991  |  View Paper
In this study we have examined the deleterious effect of serine to cysteine mutation at position 311 (S311C) in the ICL3 region that is implicated in diseases like schizophrenia and alcoholism.
Biochimie  •  2016  |  View Paper
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