Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a month ago

Possible Interaction: Cysteine and Penicillamine



Research Papers that Mention the Interaction

The supplementation of culture medium with L-cysteine abolishes the inhibitory effect of D-Pen , whilst copper sulphate synergistically inhibits PHA-induced transformation.
Scandinavian journal of rheumatology. Supplement  •  1979  |  View Paper
D-Penicillamine and L-cysteine showed a dual effect, i.e. a pronounced anti-oxidative effect was, after a given time period, followed by a significant pro-oxidative effect.
Journal of pharmaceutical and biomedical analysis  •  2011  |  View Paper
L-cysteine deprivation had profound effects on glycolysis, amino acid, and phospholipid metabolism, with sharp decreases in the levels of L-cysteine, L-cystine, and S-adenosylmethionine and a dramatic accumulation of O-acetylserine and S-methylcysteine.
The Journal of biological chemistry  •  2010  |  View Paper
Cysteine and penicillamine interact to form penicillamine‐cysteine mixed disulfide-complexes.
Profiles of drug substances, excipients, and related methodology  •  2005  |  View Paper
Addition of cysteine to the double bonds of polydehydroalanine and copolymers of dehydroalanine (DHA) and methylcysteine , alanine, leucine or gamma- methyl-L-glutamate is accompanied by increased solubility and decreased molecular weight.
Advances in experimental medicine and biology  •  1977  |  View Paper
Sulphate or cysteine inhibited the growth response of certain methionine-requiring mutants to S-methylcysteine.
Journal of general microbiology  •  1962  |  View Paper
D-Penicillamine enhanced "thermal denaturation" at a low concentration but inhibited it with increasing the concentration as well as L-cysteine.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  •  1978  |  View Paper
Using isolated aortic rings in organ baths, we now show that high concentrations of cysteine potentiate the vasorelaxant response to PA , whereas responses to Angeli's salt (AS), a known generator of NO-, were almost completely inhibited.
The Biochemical journal  •  1995  |  View Paper