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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“This substitution most likely is responsible for the lack of N-ethylmaleimide sensitivity of the yeast protein and mersalyl thus reacts with another cysteine to inhibit the transport.”
Mitochondrial phosphate transport. N-ethylmaleimide insensitivity correlates with absence of beef heart-like Cys42 from the Saccharomyces cerevisiae phosphate transport protein.“The inhibition of Ca2+-accumulation by mersalyl was reversed by cysteine , but was not by phosphate, differing from ethacrynic acid.”
“Meanwhile, cysteine (0·15 mM) was able to reverse the inhibition of Mersalyl in media with as well as without phosphate and restored the uncoupling activity of the anti-inflammatory drugs.”
“This competition between cysteine and Mersalyl is “dose-dependent”.”
“Monothiols such as cysteine HCl or glutathione, when given in relatively large doses, partially reverse the PBSH changes produced by mersalyl.”
The relation of mercurial diuresis to cellular protein-bound sulfhydryl changes in renal cells.
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