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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cysteine
drug:
Leukotriene C4
Research Papers that Mention the Interaction
“Addition of 10 mM L-cysteine significantly increased LTC4 release compared with that in its absence (about 1.7 times, in terms of mean value).”
Effects of the new 5-lipoxygenase inhibitor E6080 on leukotriene release in vitro.“The extents … peptidolysis of [3]LTC4 and [3]LTD4 by 100 µl of pulmonary edema fluid attained respective mean maximum levels of 74.5±2.9% (N=…) and 37.7±10.2% (N=4) after 30 min at 37°C and were inhibited by serine-borate and by cysteine, ….”
“The responses to leukotriene C4 and leukotriene D4 were markedly potentiated when their metabolism was inhibited by S-hexyl glutathione and L-cysteine.”
Functional characterization of receptors for cysteinyl-leukotrienes in sheep trachealis muscle.“L-Serine borate (45 mM), an inhibitor of gamma-glutamyl transpeptidase, shifted … dose-response curve of LTC4 to the left by 161-fold, and L-cysteine (6 mM), an inhibitor of aminopeptidase, … the dose-response curves of LTC4 and LTD4 to the left by 67- and 23-fold, respectively.”
“ Cysteine decreased the retention of [3H]LTC4 in brain.”
“ L-Cysteine (3 mM) enhanced the contractile activity of both LTC4 and LTD4.”
“ L-Cysteine (3mM) enhanced the contractile activity of LTC4 and LTD4.”
“ L-Cysteine , an inhibitor of aminopeptidase, prevents the formation of LTE4 from LTD4 and LTC4.”
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