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“The anti-oxidants ascorbate and cysteine (50 μM), when added to MNL prior to exposure to HOCl (25 μM), prevented the anti-proliferative effects of the oxidising agent.”
“In addition to the oxidation of methionine, HOCl caused the conversion of cysteine to cysteic acid and this product may account for the remainder of inactivated GroEL not recoverable through MsrB/A. In contrast, HOCl produced only negligible yields of 3-chlorotyrosine.”
Journal of Biological Chemistry • 2004 | View Paper
“ Cysteine , tryptophan, and methionine were proven to be the most vulnerable amino acids for degradation upon hypochlorous and peracetic acid treatment, while tyrosine was only prone to degradation in the presence of hypochlorous acid.”