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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“Supplementation of cysteine and glutamine in both concentrations separately decreased intracellular ROS and DNA damage of spermatozoa with significant increase in PMI, MMP and progressive motility compared to vitrified control group (p < .05).”
The effect of cysteine and glutamine on human sperm functional parameters during vitrification“Cleavage occurs between cysteine and glutamine and converts the glutamine into a serine which can then be glycosylated.”
“Transport of L-[3H]glutamine was inhibited by 35-65% with a 20-fold excess of glutamine, …; cysteine, alpha-(methylamino)isobutyrate, and 2-amino-2-norborane carboxylic acid had smaller inhibitory effects, although cysteine had an … effect on glutamine transport at 1,000-fold … with most other amino acids.”
“Among the correlations between a-cs differences the negative relationship between lactate and alanine and the negative correlation between cystine-cysteine and leucine, isoleucine and glutamine is significant.”
“ Cysteine uptake was greatest in sodium-containing media and was inhibited by glutamine , 2-(methylamino)-isobutyric acid (αMeAIB), serine or alanine.”
Oxidative stress increases SNAT1 expression and stimulates cysteine uptake in freshly isolated rat cardiomyocytes“ObjectiveAs is the case with glutamine , requirements for amino acids such as cysteine , taurine, and serine may be increased in stress situations.”
“Excess external GLN may act as a competitive inhibitor for the uptake of cysteine and stimulate loss of cellular cysteine, interfering this with GSH synthesis.”
“Furthermore, the kinetics of L-leucine and L-cysteine inhibition of L-glutamine uptake demonstrated that neutral amino acids sharing the same brush border transporters can effectively inhibit each other in their transport.”
“In rats fed the reference diet, glutamine solution increased the plasma concentrations of threonine and cysteine.”
“Instead the mediated entry of glutamine appears to occur exclusively by a Na+-dependent system ("N") apparently specific to amino acid amides and … system is the failure of model substrates for System A (e.g. N-methylalanine) to inhibit glutamine uptake significantly, and the failure of glutamine … L-cysteine, ….”
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