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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Cysteine and Fluorouracil

supplement:

Cysteine

Research Papers that Mention the Interaction

Pharmacokinetic studies revealed that after DFUR administration, plasma DFUR and 5-fluorouracil (5-FU) levels rapidly declined, but that, in the combination with L-cysteine , the plasma clearances of DFUR and 5-FU were slowed down considerably.
Japanese journal of cancer research : Gann  •  1989  |  View Paper
The antitumor activity of 5-fluorouracil (FU) was slightly, but not significantly, increased by l-cysteine.
Journal of Cancer Research and Clinical Oncology  •  1986  |  View Paper
The presence of L-CYS significantly inhibited the in vitro degradation of 5-FU by non-treated rat liver homogenate.
Japanese journal of pharmacology  •  1983  |  View Paper