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Last Updated: 3 months ago

Possible Interaction: Cysteine and Ethacrynic Acid

supplement:

Cysteine

Research Papers that Mention the Interaction

However, DNA binding of a Cys--> Ser p65 mutant was not inhibited by ethacrynic acid, suggesting that ethacrynic acid inhibits DNA binding by alkylating p65 at Cys.
Shock  •  2005  |  View Paper
The combination of ethacrynic acid and cysteine , itself an alkaline phosphatase inhibitor, is less inhibitory than ethacrynic acid alone.
Clinica chimica acta; international journal of clinical chemistry  •  1980  |  View Paper
L-Cysteine , glutathione, verapamil or Ca(2+)-free solution significantly inhibited the contractions induced by ethacrynic acid or N-ethylmaleimide.
European journal of pharmacology  •  2002  |  View Paper
Tissue electrolytes of inner medulla decreased much more in rats given ethacrynic acid plus cysteine.
We conclude that the addition of cysteine to intravenous infusion of ethacrynic acid greatly enhances its in vivo natriuretic potency in the rat.
Canadian journal of physiology and pharmacology  •  1990  |  View Paper
Cysteine and dithiothreitol, both disulphide reducing agents, prevented the effects of quercetin and ethacrynic acid , suggesting that sulphydryl groups may be important for the expression of Ca2+-ATPase activity.
Journal of reproduction and fertility  •  1989  |  View Paper
In three monkeys simultaneous perfusion of ECA with cysteine in 10% excess prevented this effect.
Simultaneous perfusion of 0.1 mM ECA with 0.5 mM cysteine blocked this increase in facility.
Investigative ophthalmology & visual science  •  1987  |  View Paper
Cysteine added to the incubation medium partially blocked ATPase inhibition by either EA or the known sulfhydryl inhibitor, POMB.
Biochemical pharmacology  •  1970  |  View Paper