“Moreover, the combination of DFUR and L-cysteine resulted in a marked retardation of growth of human colon tumor LS174T transplanted into nude mice.”
“Pharmacokinetic studies revealed that after DFUR administration, plasma DFUR and 5-fluorouracil (5-FU) levels rapidly declined, but that, in the combination with L-cysteine , the plasma clearances of DFUR and 5-FU were slowed down considerably.”
“Thus, the potency of DFUR was increased by L-cysteine.”