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“ Cyproterone acetate inhibited the rat adrenal 3beta-hydroxysteroid dehydrogenase-5-ene,4-ene-isomerase complex in vitro, with both pregnenolone and dehydroepiandrosterone as substrates.”
“ CA also significantly inhibited the increase in prostatic weight that occurred after 14 days of administration of ACTH (20 U⁄day), prolactin (1 mg⁄day) plus ACTH (5 mg⁄day), or prolactin (1 mg⁄day) plus DHA (0.2 mg⁄day).”