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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclosporine
supplement:
Magnesium Cation
Research Papers that Mention the Interaction
“Only during cyclosporin treatment did both ionised and total magnesium concentrations become lowered.”
Ionised and Total Magnesium Serum Concentrations in Renal and Hepatic Diseases“The findings here …:1 complexes of CsA … Mg(II) and Ce(III), with metal coordination taking place on carbonyl oxygens and substantially altering the peptide structure with respect to … residues involved and the resulting conformational changes, including cis-trans conversion of peptide bonds, are different for the two metals.”
1H and 13C-NMR and molecular dynamics studies of cyclosporin a interacting with magnesium(II) or cerium(III) in acetonitrile. Conformational changes and cis-trans conversion of peptide bonds.“The formation of complexes of cyclosporin with calcium and magnesium ions is indicated by the presence of C = O stretching bands well outside the range normally expected for the amide I absorptions of free peptides.”
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