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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclosporine
supplement:
Green Tea Extract
Research Papers that Mention the Interaction
“Nitric oxide production induces by CsA treatment was significantly suppressed by GTE and iNOS inhibitor.”
The antiproteinuric effects of green tea extract on acute cyclosporine-induced nephrotoxicity in rats.“ GTE also decreases CyA induced high TGF-beta production, which is incriminated in CyA induced nephrotoxicity.”
“ GTE is also known to attenuate CyA induced nephrotoxicity.”
“Our study demonstrates that GTE in combination with low dose CyA significantly prolongs graft survival as well as increase the production of immunosuppressive cytokine, IL-10.”
“These results indicate the potential of GTE as an adjunctive therapy in combination with CyA to prolong allograft survival and to reduce CyA induced nephrotoxicity.”
“A concomitant administration of GTE , to CsA receiving rats, markedly prevented the generation of thiobarbituric acid-reacting substances (TBARS) and significantly attenuated CsA-induced renal dysfunction as assessed by estimating serum creatinine, blood urea nitrogen, uric acid and urinary excretion of glucose.”
“Supplementation of GTE could be useful in reducing CsA nephrotoxicity in rats.”
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