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Last Updated: 2 months ago

Possible Interaction: Cyclosporine and Glycine

supplement:

Glycine

Research Papers that Mention the Interaction

Therefore, it is concluded that cyclosporin A causes renal injury by mechanisms involving hypoxia-reoxygenation, effects which can be prevented effectively by dietary glycine.
American journal of physiology. Renal physiology  •  1998  |  View Paper
Therefore, it is concluded that cyclosporin A causes renal injury by mechanisms involving hypoxia-reoxygenation, effects which can be prevented effectively by dietary glycine.
American journal of physiology. Renal physiology  •  1998  |  View Paper
Moreover, dietary glycine is protective in the kidney against cyclosporin A toxicity and ischemia-reperfusion injury.
Cellular and Molecular Life Sciences CMLS  •  1999  |  View Paper
In the presence of fructose plus glycine, CsA decreased apoptosis and delayed but did not prevent the MPT.
Hepatology  •  2004  |  View Paper
CsA infusion for 30 min increased efferent renal nerve activity 2-fold, and dietary glycine (5%) totally blocked this phenomenon.
This study was designed to elucidate the mechanism of radical production caused by CsA. Pretreatment of rats with CsA (25 mg/kg, i.g.) for 5 days decreased glomerular filtration rates by 65%, an effect largely prevented by both dietary glycine (5%) or renal denervation.
Molecular pharmacology  •  1999  |  View Paper
Dietary glycine prevented or minimized kidney damage due to cyclosporine in all parameters studied nearly completely.
Transplantation  •  1997  |  View Paper