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Discover Supplement-Drug Interactions
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Last Updated: 3 months ago
drug:
Cyclosporine
supplement:
Ginkgo Biloba Whole
Research Papers that Mention the Interaction
“ Gbe inhibited CsA induced lipid peroxidation in a concentration dependent manner.”
Influences of Ginkgo biloba on cyclosporin A induced lipid peroxidation in human liver microsomes in comparison to vitamin E, glutathione and N-acetylcysteine.“In conclusion, ginkgo and onion markedly decreased the oral bioavailability of cyclosporin.”
“Oral coadministration of ginkgo and onion significantly decreased the Cmax of cyclosporin by 62% and 60%, and reduced the AUC0-t by 51% and 68%, respectively, whereas no influence was observed when cyclosporin was given intravenously.”
“The coadministration of cyclosporin with ginkgo or onion may be subject to clinically relevant interactions as St. John's Wort.”
Marked decrease of cyclosporin bioavailability caused by coadministration of ginkgo and onion in rats.
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