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“It … cyclosporin A (CsA) nephrotoxicity can … concomitant administration of omega-3 fatty acids or vitamin E. The present study was designed to establish whether the effect of the above substances can … rats with hereditary hypertriglyceridemia (HTG) whose sensitivity to the nephrotoxic effect is greater than in control AVN rats.”
“Feeding rats diets containing omega-3 fatty acids , known to be competitive inhibitors of cyclooxygenase metabolites, prevents CsA from selectively increasing TxA2 and preserves renal function.”