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Possible Interaction: Cyclosporine and Calcium Supplement

Research Papers that Mention the Interaction

Calcium content in erythrocytes of patients receiving Sandimmun was 27.6% higher than in healthy persons.
Annals of transplantation  •  1996  |  View Paper
CsA … calcium concentration as determined by a flow cytometry assay (p < 0.05).ConclusionThe results presented in this report demonstrated that the synergistic effect of CsA … in suppressing the expression of biofilm related and drug-resistant genes, and reducing cellular surface hydrophobicity, as well as evoking intracellular calcium concentration.
BMC Microbiology  •  2016  |  View Paper
Activation was dependent on nuclear factor of activated T cells (NFAT), occurred in cells deficient in the tyrosine kinase p56(lck), and could be blocked by addition of cyclosporin A and by depletion of calcium.
Journal of virology  •  2001  |  View Paper
In single isolated endothelial cells, the thrombin-induced increase in cytosolic free calcium was enhanced by both CsA and cremophor.
Transplantation  •  1993  |  View Paper
The results support the hypothesis that the toxic effect of cyclosporin A may be mediated through an increased Ca++ influx into the proximal tubular cells.
Pharmacology & toxicology  •  1990  |  View Paper
CsA induced a time and concentration-dependent reduction in unstimulated (basal) and Ca++ ionophore (A23187)-stimulated release of PGI2.
Transplantation  •  1988  |  View Paper
CsA addition increased intracellular calcium content.
European journal of immunology  •  1987  |  View Paper
Calcium retention capacity was greater with both PoCo and CysA (1096 ±45 and 1287 ±128 nmol Ca(2+)/mg protein) than with IFR (756 ±103; p < 0.05).
Archives of medical science : AMS  •  2013  |  View Paper
Unfortunately, CsA can cause several side effects, and it can favor the excretion of calcium and magnesium.
Biophysical journal  •  2006  |  View Paper
The determination of intracellular Ca(2+) with flow cytometry showed that CsA did not prevent the increase of intracellular Ca(2+) induced by A(23187), which showed that CsA might affect the event in the downstream of calcium increase.
Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica  •  1996  |  View Paper
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