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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Cyclophosphamide and Proline

supplement:

Proline

Research Papers that Mention the Interaction

These results indicate that cyclophosphamide inhibits the synthesis of proteins, including collagen, and inhibits the hydroxylation of proline in collagen.
Acta pharmacologica et toxicologica  •  1977  |  View Paper
This indicates that cyclophosphamide may inhibit the cross-linking of collagen by blocking the aldehydes or decrease the stability of the collagen molecule by decreasing the hydroxylation of proline.
Acta pharmacologica et toxicologica  •  1975  |  View Paper
It is concluded, that daily treatment of rats with cyclophosphamide or azathioprine from 14 to 42 days seems to inhibit the catabolic processes in the skin and granulation tissue, to decrease the hydroxylation of proline in collagen, and to inhibit the intermolecular cross-linking in collagen.?222
Acta pharmacologica et toxicologica  •  1975  |  View Paper