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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclophosphamide
supplement:
Niacin
Research Papers that Mention the Interaction
“The present findings revealed that NMD supplementation might be useful to reduce CP‐associated hepatotoxicity, and thereby can increase the therapeutic utility of CP.”
Nicotinamide attenuates cyclophosphamide‐induced hepatotoxicity in SD rats by reducing oxidative stress and apoptosis“Administration of NA 15 min before CY treatment, and thereafter daily, substantially reduced the amount of apoptosis and effectively eliminated (4 apoptotic cells per 100 islets) the second wave of beta‐cell apoptosis seen at day 7 in 12‐week‐old animals given CY alone.”
“Pretreatment of rats with daily intraperitoneal injection of taurine plus niacin 7 days prior to and 2 days after cyclophosphamide insult significantly inhibited the development of lung injury, prevented the alterations in lavage fluid biomarkers associated with inflammatory reactions, with less lipid peroxidation and restoration of antioxidants.”
“ Nicotinamide has been reported to prevent the toxic and antitumour effects of ‘ Cytoxan’5.”
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