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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclophosphamide
supplement:
Indole-3-Carbinol
Research Papers that Mention the Interaction
“Limb malformation incidences were reduced …% litters affected in the CP control to 16% in the I3C/CP 48-hr treatment group, and tail malformations were reduced from 45% in … control to 16% in the I3C/CP 48-hr treatment group, indicating a protective effect of prior exposure to I3C.”
Prior exposure to indole-3-carbinol decreases the incidence of specific cyclophosphamide-induced developmental defects in mice.“The antimutagenic potential of I3C towards CP was also evident as the status of mitotic index (MI) was found to show an increment.”
“The induction of BaP and CP induced chromosomal aberrations, micronuclei formation, and sister chromatid exchanges (SCEs) were found to be inhibited in a dose-dependent manner by DAS, I3C , CUR, and BTP.”
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