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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclophosphamide
supplement:
Garlic
Research Papers that Mention the Interaction
“Three different doses of garlic extract were tested for their modulatory capacity on the mutagenecity exerted by 100 microg …(-1) of CR The results indicate a significant decrease in the frequency of CA and SCE suggesting that the garlic extract modulates … CP induced genotoxicity in a dose dependent manner.”
Modulatory effects of garlic extract against the cyclophosphamide induced genotoxicity in human lymphocytes in vitro.“However in the GE pre-treated and CP post-treated groups, a dose dependent decrease in cytogenetic damage was recorded.”
“Reduction in CP induced clastogenicity by GE was evident at 24 h and to a much greater extent at 48 h of cell cycle.”
Antimutagenic effects of garlic extract on chromosomal aberrations.“Moreover, garlic extract reduced the level of lipid peroxidation induced in the liver by cyclophosphamide administration.”
“The intraperitoneal administration of garlic (50 mg/animal, 14 days) along with cyclophosphamide reduced the toxicity of the latter considerably with an increase in life span of more than 70%.”
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