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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclophosphamide
supplement:
Folate
Research Papers that Mention the Interaction
“We found that folate supplementation decreased the frequency of the "common deletion" (4.8kb, bases 8103-12,936) in liver from untreated rats and from animals treated with cyclophosphamide but not 5-fluorouracil (5-FU).”
Dietary modulation of mitochondrial DNA deletions and copy number after chemotherapy in rats.“ Folate deficiency enhances the mutagenic but not the lymphotoxic effects of ENU, while it increases the lymphotoxic but not the mutagenic activity of cyclophosphamide.”
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