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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cyclophosphamide
supplement:
Alpha-lipoic acid
Research Papers that Mention the Interaction
“ ALA has a dose and time-dependent protective effect against the mutagenicity induced by CP.”
“However, in the groups of mice treated with different doses of ALA in the presence of CP , the percentages of CA decreased significantly with increases in mitotic activity.”
“These observations highlight the protective role of lipoic acid in CP induced cardiotoxicity.”
“Pretreatment with lipoic acid improved the semen quality and reduced the oxidative stress and DNA damage induced by CP , thereby demonstrating the protection rendered by lipoic acid.”
“These observations highlight the protective role of lipoic acid in CP induced cardiac injury.”
“Daily administration of lipoic acid for 20 or 30 days around cyclophosphamide treatment suppressed the incidence of diabetes to 30% (P < 0.05) and 33%, respectively.”
Effect of lipoic acid on cyclophosphamide-induced diabetes and insulitis in non-obese diabetic mice.
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