Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Curcumin and Tocophersolan

supplement:

Tocophersolan

Research Papers that Mention the Interaction

In vitro dissolution degree of the prepared CUR nanosuspensions using TPGS or Brij78 as stabilizer was greatly increased.
Journal of colloid and interface science  •  2017  |  View Paper
Conclusion: Cur-SLNs with TPGS and Brij78 could improve the oral bioavailability and intestinal absorption of curcumin effectively.
Drug delivery  •  2016  |  View Paper
The investigation showed that loading CCM into TPGS nanoparticles significantly enhanced its systemic absorption, increasing its Cmax, and producing a more sustained release profile, and increased apoptosis, and inhibited migration of HT-29 colon cancer cells.
Frontiers in Pharmacology  •  2020  |  View Paper
Reducing the particle size of curcumin down to ~200 nm with the presence of TPGS seems to be a promising approach to improving the therapeutic value of curcumin.
Pharmaceutics  •  2017  |  View Paper