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Last Updated: 3 months ago

Possible Interaction: Curcumin and Silymarin

supplement:

Silymarin

Research Papers that Mention the Interaction

When DLD-1 cells were pre-exposed to curcumin , followed by treatment with silymarin , the cells underwent a high amount of cell death.
Journal of Cancer  •  2016  |  View Paper
In the groups in which SLY and CUR were administered concurrently with CP, biochemical parameters, histopathological and immunohistochemical results were found to be significantly lower than in the CP-only group.
In the groups in which SLY and CUR were administered concurrently with CP, biochemical parameters, histopathological and immunohistochemical results were found to be significantly lower than in the CP-only group.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie  •  2017  |  View Paper
B-cell lymphoma 2 (Bcl-2) expressions were downregulated by CCl4; whereas concurrent treatment of Vit E and/or Cur along with Sil increased its expression.
On conclusion, the use of Vit E and/or Cur could potentiate the antiapoptotic action of Sil.
Animal biotechnology  •  2017  |  View Paper
On the other hand, Nrf2 protein expression was down regulated by CCl4 whereas concurrent treatment with vitamin E and/or curcumin along with silymarin increased this expression.
The use of vitamin E and/or curcumin potentiates the anti-apoptotic action of silymarin.
Toxicology mechanisms and methods  •  2016  |  View Paper
Finally, using a fluorescence microscope, accumulation of less curcumin has observed in the edema sac area of the larvae co-treated with curcumin and silymarin than in the larvae treated with curcumin only.
The result suggests that the protective effects of silymarin may be due to a decreased accumulation of curcumin in the fish body.
Indian journal of experimental biology  •  2011  |  View Paper