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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Curcumin and Silk



Research Papers that Mention the Interaction

Based on spectrofluorimetric analysis, curcumin most likely interacted with hydrophobic residues in silk , interacting with the beta-sheet domains formed in the hydrogels.
Acta biomaterialia  •  2015  |  View Paper
However, addition of the optimized concentration of curcumin and β-cyclodextrin to silk fibroin inhibited aggregation and preserved the random coil conformation even under aggregation inducing conditions, as demonstrated by CD and FTIR spectroscopy.
Biochimica et biophysica acta. Proteins and proteomics  •  2019  |  View Paper
Consequently, the extent of degradation of curcumin is remarkably suppressed upon encapsulation with the SF.
ACS omega  •  2017  |  View Paper
It was found that the microspheres composed of SF tended to entrap curcumin and piperine with the high entrapment and loading efficiencies, possibly due to their hydrophobic interactions.
Journal of Materials Science: Materials in Medicine  •  2013  |  View Paper