Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Curcumin and Oligomeric Procyanidin Complex

Research Papers that Mention the Interaction

Here, we test the hypothesis that dietary agents such as oligomeric proanthocyanidins OPCs ) and curcumin cooperatively modulate cancer-associated cellular mechanisms to inhibit carcinogenesis.
Moreover, several pathways, including protein export, glutathione metabolism and porphyrin metabolism were more effectively modulated by the combination of OPCs and curcumin.
Overall, by delineating the cooperative mechanisms of action of OPCs and curcumin , we make a case for the clinical co-administration of curcumin and OPCs as a treatment therapy for patients with colorectal cancer.
Scientific Reports  •  2018  |  View Paper
The presence of POPC or total brain lipid extract vesicles prevented the curcumin from inhibiting htt fibril formation.
Biochemistry  •  2019  |  View Paper
In this work, the interaction between curcumin and CopC has been investigated in detail by means of UV-vis absorption, FTIR, CD, fluorescence spectroscopic and molecular docking methods The results showed that the CopC conformation was altered by curcumin with reduction of β-sheet and increase of random coil.
International journal of biological macromolecules  •  2017  |  View Paper