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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Curcumin
supplement:
Hydroxyproline
Research Papers that Mention the Interaction
“Administration of curcumin or curcumol significantly diminished the level of hydroxyproline hydroxyproline and α-smooth muscle actin (α-SMA), also the collagen Ⅰ (Col-Ⅰ) and collagen Ⅲ (Col-Ⅲ) deposition were reduced in the HLF.”
The main active components of Curcuma zedoaria reduces collagen deposition in human lung fibroblast via autophagy.“Significant increase in inflammatory cell count, reactive oxygen species and hydroxyproline levels were decreased after curcumin pretreatment (all p < 0.05).”
Curcumin inhibits paraquat induced lung inflammation and fibrosis by extracellular matrix modifications in mouse model“The total amount of hydroxyproline was significantly enhanced (33.5%) in CUR –BG–CH group as compared with that of control.”
“ Hydroxyproline levels were significantly lower in the sham (48.3 ± 11.8 µg/mg) and the curcumin (63.8 ± 13.9 µg/mg) group compared to the control group (85.7 ± 22.1 µg/mg; p < 0.05).”
“In addition, curcumin significantly reduced the total lung hydroxyproline in BLM rats.”
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