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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Curcumin and Fish Oils


Fish Oils

Research Papers that Mention the Interaction

Mice fed with fish oil and curcumin for 1 month had more significant effects on Y-maze, and the combination showed more significant inhibition of JNK, IRS-1, and tau phosphorylation.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  2009  |  View Paper
Expression and activity of iNOS, COX-2, and 5-LOX are downregulated, and p21 is upregulated in tumor xenograft fed curcumin combined with fish oil diet when compared to individual diets.
Mice fed fish oil and curcumin showed a significantly reduced tumor volume, 25% (P < 0.04) and 43% (P < 0.005), respectively, and importantly, a combination of curcumin and fish oil diet showed > 72% (P < 0.0001) tumor volume reduction.
Nutrition and cancer  •  2008  |  View Paper
In contrast, compared with other diets, combined FO and curcumin feeding enhanced the resolution of chronic inflammation and suppressed (P < 0·05) a key inflammatory mediator, NF-κB, in the colon mucosa.
Mucosal microarray analysis revealed that dietary FO, curcumin and FO plus curcumin combination differentially modulated the expression of genes induced by DSS treatment.
The British journal of nutrition  •  2011  |  View Paper