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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Curcumin and Emodin

supplement:

Emodin

Research Papers that Mention the Interaction

Curcumin and emodin were also found to synergistically inhibit cell population and migration in SiHa and HeLa cells.
Expression of downstream effectors of TGF-β signaling pathway, cyclinD1, p21 and Pin1, was inhibited along with the down regulation of key mesenchymal markers (Snail and Slug) upon curcumin and emodin treatment.
PloS one  •  2015  |  View Paper
In this study, we report for the first time that combined curcumin and emodin administration synergistically inhibits proliferation (MTT assay), survival (flow cytometry), and invasion (transwell migration assay) of breast cancer cells.
Our results not only provide insight into the mechanism of synergy between curcumin and emodin in breast cancer cells, but also suggest a new and potentially useful approach for breast cancer therapy.
Molecular and Cellular Biochemistry  •  2013  |  View Paper