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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Curcumin
supplement:
Docosahexaenoic Acid
Research Papers that Mention the Interaction
“The dramatically low IC50 value of CUR DHA ME (3.755 ± 0.24 ng/mL) is therefore attributed to the synergistic effect of CUR and DHA in the ME.”
Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion“Taken together, these data suggest that curcumin enhances DHA synthesis, resulting in elevated brain DHA content.”
“We report that curcumin enhances the synthesis of DHA from its precursor, α-linolenic acid (C18:3 n-3; ALA) and elevates levels of enzymes involved in the synthesis of DHA such as FADS2 and elongase 2 in both liver and brain tissues.”
“The combination of curcumin and DHA was also efficient in counteracting reductions in the plasticity markers, brain-derived neurotrophic factor and its receptor p-trkB, and learning ability, which had been lessened after TBI.”
“These effects were counteracted by DHA or curcumin, whereas the combination of curcumin and DHA had an enhanced effect on DHA and 4-HNE.”
Dietary Strategy to Repair Plasma Membrane After Brain Trauma
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