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Last Updated: 3 months ago

Possible Interaction: Curcumin and Cupric Cation

supplement:

Cupric Cation

Research Papers that Mention the Interaction

Intracellular ROS was completely restored by adding Cu2+ , which can bind and modify the curcumin's physico-chemical property, and this resulted in a marked potentiation of its anti-proliferative effect.
Oncology reports  •  2016  |  View Paper
In addition, the binding ability between Cu2+ and curcumin was less than that between Cu2+ and CopC. Moreover, the binding of curcumin with Cu2+ has an effect on the binding ability between curcumin and CopC. The thermodynamic parameters ΔH and ΔS at different temperatures were obtained.
International journal of biological macromolecules  •  2017  |  View Paper
The ESA kinetics of the Cu(II)-curcumin complexes exhibit a sharp rise and a fast decay with a time constant of approximately 1 ps in both media due to the strong interaction between Cu(II ) and curcumin.
The Cu(II ) ion exhibits a high efficiency in quenching the fluorescence of curcumin.
Physical chemistry chemical physics : PCCP  •  2012  |  View Paper
Curcumin treated with CYP 2D6, CYP1A1, or CYP1A2 induced DNA damage in the presence of Cu(II).
Archives of biochemistry and biophysics  •  2002  |  View Paper
Low dosage of curcumin depressed oxidative stress levels exacerbated by Cu(II).
These results suggest that curcumin , in a concentration-dependent manner, plays both anti-oxidative and pro-oxidative roles in primary neurons treated with Cu(II).
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2011  |  View Paper
Curcumin was found to be the most effective in the DNA cleavage reaction and a reducer of Cu(II ) followed by dmC and bdmC. The rate of formation of hydroxyl radicals by the three curcuminoids also showed a similar pattern.
Chemico-biological interactions  •  1999  |  View Paper