Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“ Curcumin induced the production of reactive oxygen species (ROS) and Ca+2 , decreased the levels of mitochondria membrane potential and induced caspase-3 activity.”
“Depletion of the calcium stores in the ER by the SERCA calcium pump inhibitors thapsigargin or curcumin inhibits these interactions and allows the protein to be trafficked to the plasma membrane [Nat.”
Molecular and Cellular Biochemistry • 2020 | View Paper
“Interestingly, a recent study has provided evidence implying that curcumin inhibits pro-protein convertase zymogen maturation by decreasing Ca influx into the ER, thereby causing suppression of protein activity [5].”
European journal of pharmacology • 2006 | View Paper
“Administration of curcumin and CA abrograted this effect.”
“The antioxidant status which was decreased in alcohol, DeltaPUFA and alcohol + DeltaPUFA groups was effectively modulated by both curcumin and CA treatment.”
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques • 2004 | View Paper
“Using a Fura-2/AM calcium ion probe, we found that curcumin resisted the effects of the gp120 V3 loop on hippocampal synaptosomes and decreased Ca 2 + concentration in synaptosomes.”