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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Curcumin and Ascorbate

supplement:

Ascorbate

Research Papers that Mention the Interaction

The DNA-damaging ability of EGCG, but not curcumin , was hindered by either ascorbate or NAC, which was also shown in HT29 and SW480 colon cancer cells.
Free radical research  •  2014  |  View Paper
ESR spectroscopy demonstrated that curcumin produced radicals under alkaline conditions, scavenged the superoxide anion radical, and enhanced the radical intensity of sodium ascorbate at higher concentrations.
Anticancer research  •  1998  |  View Paper
METHODS AND RESULTS Here, …, including gallic acid, ascorbate (vitamin C), tert-butylhydroquinone (… E), dramatically increased curcumin stability in phosphate buffer at physiological pH. When treated in basal cell culture medium in MC38 colon … showed a weak antiproliferative effect; co-addition of antioxidants enhanced stability and antiproliferative effect of curcumin.
METHODS AND RESULTS Here, …, including gallic acid, ascorbate (vitamin C), tert-butylhydroquinone (… E), dramatically increased curcumin stability in phosphate buffer at physiological pH. When treated in basal cell culture medium in MC38 colon … showed a weak antiproliferative effect; co-addition of antioxidants enhanced stability and antiproliferative effect of curcumin.
Molecular nutrition & food research  •  2016  |  View Paper