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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cupric Chloride
supplement:
Sodium Ascorbate
Research Papers that Mention the Interaction
“ CuCl2 transiently stimulated the hydrogen peroxide (H2O2) production by sodium ascorbate , whereas FeCl3 slightly reduced the H2O2 production.”
“The apoptosis-inducing activity of sodium ascorbate was significantly enhanced by noncytotoxic concentrations of CuCl2 , but was almost completely eliminated by FeCl3.”
Induction of apoptosis by cooperative action of vitamins C and E.“Addition of either CuCl or CuCl2 significantly enhanced sodium ascorbate or sodium 5,6-benzylidene-L-ascorbate (SBA)-induced cytotoxicity and internucleosomal DNA cleavage in human promyelocytic leukemic HL-60 cells.”
“The cytotoxic activity of both sodium ascorbate and SBA was significantly enhanced by CuCl2 and this stimulation effect of CuCl2 was effectively chelated by DTPA.”
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