Possible Interaction: Cupric Cation and Cobaltous Cation

“Through a comparative study on the intermediate states of the zinc-bound native CA II and non-native metal-… IIs, we demonstrate that the characteristic metal ion coordination geometries (tetrahedral for Zn2+, tetrahedral to octahedral conversion for Co2+ , octahedral for Ni2+, … trigonal bipyramidal for Cu2+ ) directly modulate … catalytic efficacy.”

“A 50-times higher Co(II ) extracellular concentration hindered the Cu(II) uptake almost completely and a 10-times higher Co(II) concentration already decreased the Dp44mT-mediated Cu toxicity.”

“This effect was detected on the enzyme having Co(II) substituted for the native Zn(II), in which the resonances of residues bound to the copper are detected because of the antiferromagnetic coupling between Cu(II) and Co(II).”

“The lower susceptibility is due to antiferromagnetic coupling between Co2+ and Cu2+ , and the magnitude of the coupling constant is probably ⪢5 cm−1.”

“SDS and metal ions such as Fe2+, Cu2+ , Mg2+, Co2+ , Mn2+, and Ca2+ decreased the enzyme activity remarkably, whereas the addition of Na+ and K+ led to an increase in activity.”

“Addition of Cu(II) increased the toxicity of Co(II ) and Ni(II); in contrast, Ni(II) toxicity was diminished in the presence of Fe(II).”

“The reducing power of the Co(II ) and Cu(II) complexes have been checked and compared.”

“In a ternary system, increasing Co(II) concentration exhibited protection against the inhibitory effect of Cu(II) on Zn(II) sorption.”

“A synergistic effect of Cu(II) with a second metal ion (Ni(II), Co(II ) or Mn(II) traces) was observed.”

“The experiments reveal that while there … effect of K+, Cd2+, Co2+ , Mg2+, and Ni2+, there is a … collapse pressure in the presence of Cu(II) cation , showing that monolayers of L-RA-Pro, formed at the air-water … selectivity for copper(II) ions with regard to other cations tested.”