Possible Interaction: Creatinine and Vitamin C

“ Vitamin C also interferes with creatinine assay using Jaffe and enzymatic methods.”

“ Vitamin C supplementation improves endothelial function and creatinine clearance.”

“Results: With a serum ascorbic acid concentration of 12.0 mmol/L, the values for sodium, potassium, calcium and creatinine increased by 43%, 58%, 103% and 26%, respectively (P<0.01).”

“At therapeutic concentrations, ascorbic acid distinctly interferes with the analysis of glucose, uric acid, creatinine and inorganic phosphate.”

“The ascorbic acid lowers the glucose and the bilirubine values; it increases the creatinine and the uric acid concentration.”

“Compared to the HS group, VC treatment led to a remarkable reduction in the kidney pathological score and CRE ,BUN,TNF-α, and IL-1β levels (P < 0.05), and a significant increase in Vitamin C, SOD, and RAFHR levels in the plasma (P < 0.05).”

“However, kidney and lens LP levels, and plasma glucose, urea and creatinine values were decreased by VCE supplementation.”

“ Vitamin C pre-treatment significantly decreased the urea nitrogen and creatinine levels.”

“Treatment with vitamin C or with vitamins C and A significantly decreased the MDA levels and serum NO, urea and creatinine levels, recovered the antioxidant enzyme activities (SOD, GSH-Px and CAT), and prevented the renal tissue damage in endotoxemic rats.”