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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Creatinine
supplement:
Glycine
Research Papers that Mention the Interaction
“In two patients, rates of incorporation of 14-C glycine into urinary creatinine were increased by 10% and 11%, while rates of incorporation into uric acid were increased 84% and 159%, respectively, as a result of fructose infusion.”
Stimulation of human purine synthesis de novo by fructose infusion.“The results suggest that guanidine, methylguanidine, creatinine , and guanidinosuccinic acid inhibited responses to the inhibitory neurotransmitters GABA and glycine by blocking the chloride channel.”
Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture“Rats loaded with creatinine by intraperitoneal injection demonstrated a 30% reduction in GAA methylation and a 45% reduction in total synthesis of creatine from glycine.”
Creatine Synthesis After Creatinine Loading and After Nephrectomy.∗
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