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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Creatinine and Glycine

supplement:

Glycine

Research Papers that Mention the Interaction

In two patients, rates of incorporation of 14-C glycine into urinary creatinine were increased by 10% and 11%, while rates of incorporation into uric acid were increased 84% and 159%, respectively, as a result of fructose infusion.
Metabolism: clinical and experimental  •  1975  |  View Paper
The results suggest that guanidine, methylguanidine, creatinine , and guanidinosuccinic acid inhibited responses to the inhibitory neurotransmitters GABA and glycine by blocking the chloride channel.
Annals of neurology  •  1990  |  View Paper
Rats loaded with creatinine by intraperitoneal injection demonstrated a 30% reduction in GAA methylation and a 45% reduction in total synthesis of creatine from glycine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1960  |  View Paper