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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Creatinine
supplement:
Glycerol
Research Papers that Mention the Interaction
“Equilibration of creatinine and urea was slower and creatinine clearance lower with glycerol.”
Short-term studies on the use of glycerol as an osmotic agent in continuous ambulatory peritoneal dialysis (CAPD).“RESULTS Intramuscular injection of gl cerol si gnificantly increased blood BUN, Cre , G OT, GPT and CPK levels and induced severe histopathologic damage in the kidneys.”
Recombinant human erythropoietin reduces rhabdomyolysis-induced acute renal failure in rats.“RESULTS Intramuscular injection of gl cerol si gnificantly increased blood BUN, Cre , G OT, GPT, CPK levels and induced severe histopathologic damage in the kidneys.”
“And, glycerol increased the production of NO, TNF-alpha, creatinine , and MDA, and decreased SOD.”
“Both drugs attenuated the reduction in creatinine clearance (control 431.8 +/- 108.2, glycerol 96.7 +/- 43.8, glycerol plus nifedipine 264.9 +/- 103.5, and glycerol plus BN 52021 188.9 +/- 69.8 microL/min/100 g, p < 0.001).”
“ Creatinine clearance was impaired at 3 hours after glycerol administration, but intrarenal All, PRA, and KRC were not different from controls.”
“Following the treatment of glycerol, creatinine clearance was significantly decreased, and high anion gap metabolic acidosis developed.”
Altered Regulation of type 3 Na+/H+ exchanger, type 1 Na+/HCO3- cotransporter, and Na+,K+-ATPase in the Kidney of Rats with Experimental Rhabdomyolysis
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