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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Creatinine
supplement:
Fluorides
Research Papers that Mention the Interaction
“ Serum fluoride concentrations were correlated with creatinine clearance and fluoride supply.”
Fluoride exposure and bone status in patients with chronic intestinal failure who are receiving home parenteral nutrition.“We found that fluoride elimination was inversely related to creatinine clearance.”
“Patients over 65 years of age achieved higher bone fluoride (F) levels and a significantly greater increase in bone … patients (32.8 vs. 17.9%, p < 0.01), associated with an age‐related decline in renal function; serum fluoride was significantly … correlated to creatinine clearance (r = −0.… < 0.01).”
“A positive correlation between creatinine and fluoride clearance was found.”
“ Fluoride exposure altered tissue biochemistry (protein, acid phosphatase and alkaline phosphatase content) and increased urea (23-58%) and creatinine content (14-127%) in the serum.”
Protective role of diet supplements Spirulina and Tamarind fruit pulp on kidney in sodium fluoride exposed Swiss albino mice: Histological and biochemical indices.“…,fluoride caused degeneration and necrosis of the tubular cells, renal … renal function parameters including elevated contents of serum creatinine ( Cr ), serum uric acid (UA), blood urea nitrogen (BUN), and the activities of urinary N-acetyl-… sodium-potassium adenosine triphosphatase (Na+/K+-ATPase) and acid phosphatase (ACP) in the kidney.”
Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride“…,fluoride caused degeneration and necrosis of the tubular cells, renal … renal function parameters including elevated contents of serum creatinine ( Cr ), serum uric acid (UA), blood urea nitrogen (BUN), and the activities of urinary N-acetyl-… sodium-potassium adenosine triphosphatase (Na+/K+-ATPase) and acid phosphatase (ACP) in the kidney.”
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