Possible Interaction: Creatinine and Calcium Supplement

“Children had a much higher excretion of calcium , oxalate and citrate when adjusted for creatinine.”

“Serum levels of alkaline …=0.040), creatinine (85.2±17.1 versus75.1±12.8 mmol/L, P=0.021), uric acid (401.9±114.2 versus …, but carbondioxide combining power (CO2CP, 26.7±4.4 versus 28.9±4.5 mmol/L, P=0.042) and serous calcium (….”

“They included (1) serum calcium … of normal, (2) 24-h urinary calcium …) creatinine clearance is reduced by 30%, (4) bone mineral density (T-score) reduced 2.5 SD below the peak … 50 years of age, and (6) patients for whom medical surveillance was either not desirable or not possible.”

“ Urinary calcium to creatinine ratio was significantly lower in the prehypertensive group (0.06+/-0.03 vs 0.24+/-0.13, P<0.001).”

“When the creatinine clearance was below 50 ml/min, the net excretion of Na+ and Ca++ was drastically reduced.”

“ Urinary calcium increased from 473±186 to 662±213 mmol per mol creatinine (p<0.05).”

“ CA and MCT correlated significantly with creatinine clearance in the entire population (r = 0.43; P = 0.005; r = 0.35; P = 0.02, respectively).”

“The intra-individual variation of calcium and the concentration of creatinine in serum correlate significantly (r = 0.661, p less than 0.01).”

“In both groups Ca was negatively correlated with creatinine , but the slope of the regression line was steeper in the AAN group than in controls.”

“Fasting urinary calcium in the steroid group [166.1 +/- 78.5 (+/- SD) mg/g creatinine ] was about 2 times greater than that in control subjects (74.1 +/- 35.6) (p less than 0.001).”