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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Creatine and Triiodothyronine



Research Papers that Mention the Interaction

T3 … creatine compared with the placebo group, respectively, for body mass (1.86 and -1.01 kg), fat-free mass (2.22 and 0.00 kg), … (9-15 and -6 to 1%), lower-body mean power (11 and 0%), and lower-extremity functional capacity (6-9 and 1-2%).
Medicine and science in sports and exercise  •  2002  |  View Paper
We exposed myoblasts to triiodothyronine T3 ) in the presence of 0.5mM creatine simultaneously for 48 h. As Figure 3 shows, this increased cellular [creatine] by up to 200%.
Biochemical Society transactions  •  1993  |  View Paper
Although the uptake of radioactive creatine of denervated muscles was significantly lower than that of controls, inhibitory action of T3 on creatine uptake was similarly observed in denervated muscles as well as in normal ones.
The results indicate that T3 has a direct effect on muscle cell per se and the inhibitory action of T3 on creatine uptake by the muscle is closely related to T3 action on the energy-requiring process in cell membrane.
The uptake of radioactive creatine of all muscles studied significantly diminished after T3 (100 microgram/100 g, s.c.)
The Japanese journal of physiology  •  1978  |  View Paper
Creatine content in muscles decreased significantly 48 h after T3 injection.
The American journal of physiology  •  1977  |  View Paper
T3 increased the plasma creatine level both in bilateral nephrectomized and in bilateral nephrectomized plus beta-GPA administrated groups.
The Japanese journal of physiology  •  1976  |  View Paper