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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Creatine and Sirolimus

supplement:

Creatine

Research Papers that Mention the Interaction

The pretreatment of mice with LY294002 (10 nmol/mouse, icv, PI3K inhibitor), wortmannin (0.… μg/mouse, icv, PI3K inhibitor), ZnPP (10 μg/mouse, icv, HO-1 inhibitor), or rapamycin (0.2 nmol/mouse, icv, mTOR …) prevented the antidepressant-like effect of creatine (1 mg/kg, po) in the TST.
Molecular Neurobiology  •  2015  |  View Paper
Rapamycin inhibited the cardioprotective effect of isoflurane: myocardial infarction increased to 44 ± 4% and creatine kinase-MB level increased to 254 ± 9% above baseline.
Anesthesiology  •  2008  |  View Paper