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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In the assay system of endothelial permeability, supplementation with 5 mM CR significantly suppressed the endothelial permeability induced by serotonin and H2O2.”
Anti‐inflammatory activity of creatine supplementation in endothelial cells in vitro“Our results indicate that Cr plays a complex role in affective disorders and 5-HT , warranting further investigation.”
Creatine transporter knockout mice (Slc6a8) show increases in serotonin-related proteins and are resilient to learned helplessness“With combined creatine and exercise, 5-HT positive cells increased significantly and had a synergic effect on both DR and MnR. [Conclusion] The present study found that even a single treatment of creatine or exercise has partial effects as an antidepressant in mice with chronic mild stress-induced depression.”
Effects of creatine monohydrate supplementation and exercise on depression-like behaviors and raphe 5-HT neurons in mice
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