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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Creatine and Serotonin

supplement:

Creatine

Research Papers that Mention the Interaction

In the assay system of endothelial permeability, supplementation with 5 mM CR significantly suppressed the endothelial permeability induced by serotonin and H2O2.
British journal of pharmacology  •  2003  |  View Paper
Our results indicate that Cr plays a complex role in affective disorders and 5-HT , warranting further investigation.
Behavioural Brain Research  •  2020  |  View Paper
With combined creatine and exercise, 5-HT positive cells increased significantly and had a synergic effect on both DR and MnR. [Conclusion] The present study found that even a single treatment of creatine or exercise has partial effects as an antidepressant in mice with chronic mild stress-induced depression.
Journal of exercise nutrition & biochemistry  •  2016  |  View Paper