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Last Updated: 2 years ago

Possible Interaction: Creatine and Ornithine

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supplement:

Creatine

supplement:

Ornithine

Research Papers that Mention the Interaction

“In consequence endogenous creatine production probably is severely decreased because of inhibition of the rate-limiting transamidination step by ornithine.”

Inhibition of arginine-glycine amidinotransferase by ornithine. A possible mechanism for the muscular and chorioretinal atrophies in gyrate atrophy of the choroid and retina with hyperornithinemia.

Biochimica et biophysica acta • 1980 | View Paper

“We conclude that in gyrate atrophy patients, formation of guanidinoacetate, creatine , and possibly phosphocreatine is inhibited at the transaminidation step by the high concentrations of ornithine.”

Gyrate atrophy of the choroid and retina with hyperornithinemia. Deficient formation of guanidinoacetic acid from arginine.

The Journal of clinical investigation • 1980 | View Paper

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