Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Creatine and Isoproterenol

supplement:

Creatine

Research Papers that Mention the Interaction

Results showed that ISO induced a remarkable alteration of electrocardiogram (ECG) pattern and increases of plasma cardiac troponin T, creatine kinase-MB, total cholesterol, triglycerides, low-density lipoprotein-cholesterol, lactate dehydrogenase, aspartate transaminase, and malondialdehyde.
Journal of biochemical and molecular toxicology  •  2021  |  View Paper
These results indicate that the cardionecrotic action evoked in vivo by isoprenaline and its reduction by creatinol O-phosphate may be attributed to a direct action on the myocardial cell.
Arzneimittel-Forschung  •  1979  |  View Paper
Creatinol O-phosphate increased the contractility evoked by isoprenaline 10(-5) mol/l and impaired the development of the negative inotropic effect evoked by prolonged treatment with this large dose.
Arzneimittel-Forschung  •  1979  |  View Paper
Isoprenaline-induced cardionecrosis and the associated alterations of the ionic composition of the heart were reduced when Creatinol O-phosphate was injected 4 hr before isoprenaline.
Archives internationales de pharmacodynamie et de therapie  •  1979  |  View Paper